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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -BMI1 (BMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51)

Anti -BMI1 (BMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger
protein 4, RING finger protein 51)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IF
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Catalog #030810
ApplicationsSuitable for use in Western Blot, Immunofluorescence, ELISA.
Recommended DilutionELISA: 1:1000
Western Blot: 1:100~250
Immunofluorescence: 1:10~50
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No282CT3.7.6
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenBMI1 Mab is generated from mouse immunized with BMI1 recombinant protein.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesBMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51


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