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Specifications

Clone Host Grade Applications Monoclonal Mouse Ascites E B

This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimer's disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene.
Catalog #	030832
Applications	Suitable for use in Western Blot, ELISA.
Recommended Dilution	ELISA: 1:1,000
	Western Blot: 1:100~1600
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2a
Clone No	626CT4.3.8
Host	Mouse
Source	Human
Concentration	Crude ascites
Form	Supplied as a liquid, crude ascites with 0.09% sodium azide.
Purity	Ascites
Immunogen	CAT Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human CAT.
Specificity	Human, mouse
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names	CAT, Catalase