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Anti -CTNNB1, CT (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)
Anti -CTNNB1, CT (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E B |
|
| The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. | | | Catalog # | 030898 | | Applications | Suitable for use in Western Blot, ELISA. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:500~4000 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 691CT11.2.1 | | Host | Mouse | | Source | Human | | Concentration | Crude ascites | | Form | Supplied as a liquid, crude ascites with 0.09% sodium azide. | | Purity | Ascites | | Immunogen | CTNNB1 Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human CTNNB1. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CTNNB1, CTNNB, Catenin beta-1, Beta-catenin |
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