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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -DDR2 (DDR2, NTRKR3, TKT, TYRO10, Discoidin domain-containing receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Ty

Anti -DDR2 (DDR2, NTRKR3, TKT, TYRO10, Discoidin domain-containing receptor 2, CD167
antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2,
Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Ty

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq].
Catalog #030909
ApplicationsSuitable for use in Western Blot, ELISA.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100~1600
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No484CT5.5.4
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid, crude ascites with 0.09% sodium azide.
PurityAscites
ImmunogenPurified His-tagged DDR2 protein (fragment).
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDDR2, NTRKR3, TKT, TYRO10, Discoidin domain-containing receptor 2, CD167 antigen-like family member B, Discoidin domain-containing receptor tyrosine kinase 2, Neurotrophic tyrosine kinase, receptor-related 3, Receptor protein-tyrosine kinase TKT, Tyrosine


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