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Anti -HLA-DRA (HLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA)
Anti -HLA-DRA (HLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain,
MHC class II antigen DRA)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E B |
|
| HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. | | | Catalog # | 031024 | | Applications | Suitable for use in Western Blot, ELISA. | | Recommended Dilution | ELISA: 1:1000 | | Western Blot: 1:500~16000 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgM | | Clone No | 302CT2.3.2 | | Host | Mouse | | Source | Human | | Concentration | Crude ascites | | Form | Supplied as a liquid, crude ascites with 0.09% sodium azide. | | Purity | Ascites | | Immunogen | HLA-DRA Mab is generated from mouse immunized with HLA-DRA recombinant protein. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | HLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA |
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