Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to HLA » Anti -HLA-DRA (HLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA)

Anti -HLA-DRA (HLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain,
MHC class II antigen DRA)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5.
Catalog #031025
ApplicationsSuitable for use in Western Blot, ELISA.
Recommended DilutionELISA: 1:1000
Western Blot: 1:100
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgM,k
Clone No302CT2.3.2
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenHLA-DRA Mab is generated from mouse immunized with HLA-DRA recombinant protein.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesHLA-DRA, HLA-DRA1, HLA class II histocompatibility antigen, DR alpha chain, MHC class II antigen DRA


External Links