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You are here:Home » Antibodies » Abs to Enzymes, Oxidase » Anti -LOX , ID (LOX, Protein-lysine 6-oxidase, Lysyl oxidase)

Anti -LOX , ID (LOX, Protein-lysine 6-oxidase, Lysyl oxidase)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
Catalog #031090
ApplicationsSuitable for use in Western Blot, ELISA.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100~500
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No624CT23.7.3
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenLOX Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human LOX.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesLOX, Protein-lysine 6-oxidase, Lysyl oxidase


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