Anti -MMP2 (MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix
metalloproteinase-2, TBE-1, PEX)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E B IH |
|
| Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. | | | Catalog # | 031129 | | Applications | Suitable for use in Western Blot, Immunohistochemistry, ELISA. | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:200-1000 | | Immunohistochemistry: 1:50~100 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b,k | | Clone No | 6E3F8 | | Host | Mouse | | Source | Human | | Concentration | Ascites | | Form | Supplied as a liquid, crude ascites with 0.09% sodium azide. | | Purity | Ascites | | Immunogen | MMP2 antibody is generated from mouse immunized with MMP2 recombinant protein. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX |
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