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You are here:Home » Antibodies » Abs to Homeobox (HOX) » Anti -NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog)

Anti -NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity).
Catalog #031151
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA.
Recommended DilutionELISA: 1:1000
Western Blot: 1:100~250
Immunohistochemistry: 1:10~50
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No60CT77.1.1
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenNANOG Mab is generated from mouse immunized with NANOG recombinant protein.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesNANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog


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