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Anti -NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog)
Anti -NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B IH |
|
| Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity). | | | Catalog # | 031151 | | Applications | Suitable for use in Western Blot, Immunohistochemistry, ELISA. | | Recommended Dilution | ELISA: 1:1000 | | Western Blot: 1:100~250 | | Immunohistochemistry: 1:10~50 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1,k | | Clone No | 60CT77.1.1 | | Host | Mouse | | Source | Human | | Concentration | 0.25mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | NANOG Mab is generated from mouse immunized with NANOG recombinant protein. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog |
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