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You are here:Home » Antibodies » Abs to Nephrin » Anti -Nephrin (NPHN, CNF, Nephrosis 1 Congenital Finnish Type, NPHS1, Renal Glomerulus-specific Cell Adhesion Receptor)

Anti -Nephrin (NPHN, CNF, Nephrosis 1 Congenital Finnish Type, NPHS1, Renal
Glomerulus-specific Cell Adhesion Receptor)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IF
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
Catalog #031156
ApplicationsSuitable for use in Western Blot, Immunofluorescence, ELISA.
Recommended DilutionELISA: 1:1000
Western Blot: 1:100~200
Immunofluorescence: 1:10~50
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgM,k
Clone No174CT2.1.1
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid, crude ascites with 0.09% sodium azide.
PurityAscites
ImmunogenNephrin Mab was raised using purified His-tagged recombinant human Nephrin.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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