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You are here:Home » Antibodies » Abs to Protease Inhibitors » Anti -SERPINC1 (SERPINC1, AT3, Antithrombin-III, Serpin C1)

Anti -SERPINC1 (SERPINC1, AT3, Antithrombin-III, Serpin C1)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Catalog #031245
ApplicationsSuitable for use in Western Blot, ELISA.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100~500
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No435CT4.7.4
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenPurified His-tagged SERPINC1 protein (fragment).
SpecificityHuman, rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesSERPINC1, AT3, Antithrombin-III, Serpin C1


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