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You are here:Home » Antibodies » Abs to Cardiac Markers » Anti -TNINI3 (TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I)

Anti -TNINI3 (TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
Catalog #031300
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500 - 1:8,000.
Optimal dilution to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgM
Clone No358CT10.3.6
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid (crude ascites) containing 0.09% sodium azide.
PurityAscites
ImmunogenKLH-conjugated synthetic peptide corresponding to a portion of amino acids within aa 52-79 of human TNINI3
SpecificityRecognizes human TNINI3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I


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