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You are here:Home » Antibodies » Abs to Receptors, Tyrosine Kinase » Anti -ZAP70 (ZAP70, SRK, Tyrosine-protein kinase ZAP-70, 70kD zeta-chain associated protein, Syk-related tyrosine kinase)

Anti -ZAP70 (ZAP70, SRK, Tyrosine-protein kinase ZAP-70, 70kD zeta-chain associated
protein, Syk-related tyrosine kinase)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
Catalog #031340
ApplicationsSuitable for use in Western Blot, ELISA.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100~500
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No510CT8.1.2
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid, crude ascites with 0.09% sodium azide.
PurityAscites
ImmunogenPurified His-tagged ZAP70 protein (fragment).
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesZAP70, SRK, Tyrosine-protein kinase ZAP-70, 70kD zeta-chain associated protein, Syk-related tyrosine kinase


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