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031450 Rabbit Anti-5HT3E, ID (HTR3E, 5-hydroxytryptamine receptor 3E, Serotonin receptor 3E)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_872395.2; A5X5Y0
Gene ID
285242
Gene #
HTR3E
Shipping Temp
Blue Ice
Storage Temp
-20°C
HTR3E, 5-hydroxytryptamine receptor 3E, Serotonin receptor 3E

The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
5HT3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-162 amino acids from the Central region of human 5HT3E.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010)|Hammer, C., et al. Pharmacogenomics 11(7):943-950(2010)|Lennertz, L., et al. Eur Neuropsychopharmacol 20(6):414-420(2010)|Goecke, T.W., et al. Acta Obstet Gynecol Scand 89(1):7-14(2010)|Schuhmacher, A., et al. Pharmacogenet. Genomics 19(11):843-851(2009)
USBio References
No references available
Conjugates
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