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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -ABCC11, NT (ABCC11, MRP8, ATP-binding cassette sub-family C member 11, Multidrug resistance-associated protein 8)

Anti -ABCC11, NT (ABCC11, MRP8, ATP-binding cassette sub-family C member 11, Multidrug
resistance-associated protein 8)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1.
Catalog #031475
ApplicationsSuitable for use in Western Blot, Immunohistochemistry
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenABCC11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350~380 amino acids from the N-terminal region of human ABCC11.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesABCC11, MRP8, ATP-binding cassette sub-family C member 11, Multidrug resistance-associated protein 8


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