ABP1, NT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

P19801

Isotype

IgG

Grade

Affinity Purified

Applications

E WB

Crossreactivity

Accession #

NP_001082.2

Gene ID

Gene #

ABP1

Shipping Temp

Blue Ice

Storage Temp

-20°C

ABP1, AOC1, DAO1, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein, Histaminase, Kidney amine oxidase

This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Applications

Suitable for use in Western Blot and ELISA. Other applications not tested.

Recommended Dilution

Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 71-100 in the N-terminal region of human ABP1.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human ABP1.

References

1. Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) 2. McGrath, A.P., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) 3. Chambers, J.C., et al. Nat. Genet. 42(2):149-152(2010) 4. McGrath, A.P., et al. Biochemistry 48(41):9810-9822(2009) 5. Song, W.B., et al. World J. Gastroenterol. 15(31):3916-3919(2009)

USBio References

No references available

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031508 Rabbit Anti-ABP1, NT (ABP1, AOC1, DAO1, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein, Histaminase, Kidney amine oxidase)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

ABP1, AOC1, DAO1, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein, Histaminase, Kidney amine oxidase

References

USBio References

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