ABRA, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

Q8N0Z2

Isotype

IgG

Grade

Affinity Purified

Applications

E IHC WB

Crossreactivity

Accession #

NP_631905.1;

Gene ID

137735

Gene #

ABRA

Shipping Temp

Blue Ice

Storage Temp

-20°C

ABRA, Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling

ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling (By similarity).

Applications

Suitable for use in Western Blot, Immunohistochemistry, ELISA

Recommended Dilution

ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

ABRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-312 amino acids from the C-terminal region of human ABRA.

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A affinity chromatography.

Specificity

Human

References

Lamon, S., et al. J. Physiol. (Lond.) 587 (PT 8), 1795-1803 (2009) : Kuwahara, K., et al. J. Clin. Invest. 117(5):1324-1334(2007) Kuwahara, K., et al. Mol. Cell. Biol. 25(8):3173-3181(2005) Arai, A., et al. J. Biol. Chem. 277(27):24453-24459(2002) Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

USBio References

No references available

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031509 Rabbit Anti-ABRA, CT (ABRA, Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

ABRA, Actin-binding Rho-activating protein, Striated muscle activator of Rho-dependent signaling

References

USBio References

Conjugates

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