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You are here:Home » Antibodies » Abs to Enzymes » Anti -ACACA, CT (ACACA, ACAC, ACC1, ACCA, Acetyl-CoA carboxylase 1, ACC-alpha, Biotin carboxylase)

Anti -ACACA, CT (ACACA, ACAC, ACC1, ACCA, Acetyl-CoA carboxylase 1, ACC-alpha, Biotin
carboxylase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.
Catalog #031516
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenACACA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2009-2039 amino acids from the C-terminal region of human ACACA.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesACACA, ACAC, ACC1, ACCA, Acetyl-CoA carboxylase 1, ACC-alpha, Biotin carboxylase


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