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You are here:Home » Antibodies » Antibodies-Protein Kinases » Anti -ACK1, ID (Y284) (TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2) (AP)

Anti -ACK1, ID (Y284) (TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor
protein 2) (AP)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Catalog #031537-AP
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityStore product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note Applications are based on unconjugated antibody.
Clone TypePolyclonal
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
PurityPurified by Protein A affinity chromatography.
ImmunogenACK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the Central region of human ACK1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2

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