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You are here:Home » Antibodies » Abs to Protein Kinases » Anti -ACK1, ID (Y284) (TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2) (PE)

Anti -ACK1, ID (Y284) (TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor
protein 2) (PE)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Catalog #031537-PE
ApplicationsSuitable for use in Western Blot, FLISA
Recommended DilutionFLISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze R-Phycoerythrin conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to R-Phycoerythrin (R-PE).
PurityPurified by Protein A affinity chromatography.
ImmunogenACK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the Central region of human ACK1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2


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