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Anti -ACK1, phosphorylated (Y826) (TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2)
Anti -ACK1, phosphorylated (Y826) (TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase
non-receptor protein 2)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E Gel |
|
| ACK1 is a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. | | | Catalog # | 031538 | | Applications | Suitable for use in Dot Blot, ELISA | | Recommended Dilution | ELISA: 1:1,000 | | Dot Blot 1:500 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | 0.25mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | Phospho-ACK1-Y826 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 814~844 amino acids surrounding Y826 of human ACK1. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | TNK2, ACK1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2 |
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