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You are here:Home » Antibodies » Abs to Hormones, Steroids » Anti -ACTH, phosphorylated (S168) (POMC, Pro-opiomelanocortin, Corticotropin-lipotropin, NPP, Melanotropin gamma, Gamma-MSH, Potential peptide, Corticotropin, Adrenocorticotropic hormone, Melanotropin alpha, Alpha-MSH, Corticotropin-like intermediary peptide, L

Anti -ACTH, phosphorylated (S168) (POMC, Pro-opiomelanocortin, Corticotropin-lipotropin,
NPP, Melanotropin gamma, Gamma-MSH, Potential peptide, Corticotropin, Adrenocorticotropic
hormone, Melanotropin alpha, Alpha-MSH, Corticotropin-like intermediary peptide, L

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq].
Catalog #031571-FITC
ApplicationsSuitable for use in Dot Blot, FLISA
Recommended DilutionFLISA: 1:1,000
Dot blot 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.
PurityPurified by Protein A affinity chromatography.
ImmunogenPhospho-ACTH-pS168 Antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding S168 of human ACTH.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPOMC, Pro-opiomelanocortin, Corticotropin-lipotropin, NPP, Melanotropin gamma, Gamma-MSH, Potential peptide, Corticotropin, Adrenocorticotropic hormone, Melanotropin alpha, Alpha-MSH, Corticotropin-like intermediary peptide, Lipotropin beta, Beta-LPH, Lip


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