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You are here:Home » Antibodies » Abs to Activin » Anti -Acvr2b, ID (Acvr2b, Activin receptor type-2B, Activin receptor type IIB)

Anti -Acvr2b, ID (Acvr2b, Activin receptor type-2B, Activin receptor type IIB)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Catalog #031594
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMouse Acvr2b antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of Mouse Acvr2b.
SpecificityRecognizes human Activin Receptor Type IIB at ~55kD. Species crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAcvr2b, Activin receptor type-2B, Activin receptor type IIB


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