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You are here:Home » Antibodies » Abs to Protein Kinases » Anti -ACVRL1, NT (ACVRL1, ACVRLK1, ALK1, Serine/threonine-protein kinase receptor R3, Activin receptor-like kinase 1, TGF-B superfamily receptor type I)

Anti -ACVRL1, NT (ACVRL1, ACVRLK1, ALK1, Serine/threonine-protein kinase receptor R3,
Activin receptor-like kinase 1, TGF-B superfamily receptor type I)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IH FC
ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Catalog #031596
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Flow Cytometry. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:1000
Flow Cytometry: 1:10-1:50
Immunohistochemistry (FFPE): 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Ammonium Sulfate Precipitation.
ImmunogenSynthetic peptide corresponding to aa38-68 from the N-terminal region of human ACVRL1, conjugated to KLH (P37023).
SpecificityRecognizes human ACVRL1. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesACVRL1, ACVRLK1, ALK1, Serine/threonine-protein kinase receptor R3, Activin receptor-like kinase 1, TGF-B superfamily receptor type I


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