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You are here:Home » Antibodies » Abs to Angiotensin, Angiotensinogen » Anti -AGTR1, ID (AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B, Type-1 angiotensin II receptor, AT1AR, AT1BR, Angiotensin II type-1 receptor) (Azide free) (HRP)

Anti -AGTR1, ID (AGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B, Type-1 angiotensin II receptor,
AT1AR, AT1BR, Angiotensin II type-1 receptor) (Azide free) (HRP)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC IF
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].
Catalog #031708-HRP
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Immunofluorescence: 1:10-50
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze horseradish peroxidase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added (Azide free). Conjugated to HRP.
PurityPurified by Protein A affinity chromatography.
ImmunogenAGTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-248 amino acids from the Central region of human AGTR1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAGTR1, AGTR1A, AGTR1B, AT2R1, AT2R1B, Type-1 angiotensin II receptor, AT1AR, AT1BR, Angiotensin II type-1 receptor


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