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You are here:Home » Antibodies » Abs to Enzymes » Anti -AHCY, NT (AHCY, SAHH, Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase)

Anti -AHCY, NT (AHCY, SAHH, Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH FC
S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Catalog #031712
AHCY deficiency is one of the causes of hypermethioninemia, a rare disease affecting brain development and muscle strength. Down-regulation of AHCY is also associated with certain forms of cancer, Huntington's disease and Wilson's disease.
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
ImmunogenAHCY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-118 amino acids from the N-terminal region of human AHCY.
SpecificityMouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAHCY, SAHH, Adenosylhomocysteinase, S-adenosyl-L-homocysteine hydrolase


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