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031727 Rabbit Anti-AIM2, NT (AIM2, Interferon-inducible protein AIM2, Absent in melanoma 2)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
O14862
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IF WB
Crossreactivity
Hu
Gene ID
9447
Gene #
AIM2
Shipping Temp
Blue Ice
Storage Temp
-20°C
AIM2, Interferon-inducible protein AIM2, Absent in melanoma 2

AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.

Applications
Suitable for use in Western Blot, Immunofluorescence, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Immunofluorescence: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 4-32 in the N-terminal region of human AIM2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human AIM2.
References
1. Patsos, G., et al. Int. J. Cancer 126(8):1838-1849(2010) 2. Patsos, G., et al. Glycobiology 19(7):726-734(2009) 3. Fernandes-Alnemri, T., et al. Nature 458(7237):509-513(2009) 4. Hornung, V., et al. Nature 458(7237):514-518(2009) 5. Woerner, S.M., et al. Genes Chromosomes Cancer 46(12):1080-1089(2007) 5. Cresswell, K.S., et al. Biochem. Biophys. Res. Commun. 326(2):417-424(2005)
USBio References
No references available
Conjugates
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