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031728 Rabbit Anti-AIP, CT (AIP, XAP2, AH receptor-interacting protein, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, Immunophilin homolog ARA9)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_003968.2; O00170
Gene ID
9049
Gene #
AIP
Shipping Temp
Blue Ice
Storage Temp
-20°C
AIP, XAP2, AH receptor-interacting protein, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, Immunophilin homolog ARA9

The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
AIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-321 amino acids from the C-terminal region of human AIP.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Daly, A.F., et al. J. Clin. Endocrinol. Metab. 95 (11), E373-E383 (2010) :|Stratakis, C.A., et al. Clin. Genet. 78(5):457-463(2010)|Occhi, G., et al. Eur. J. Endocrinol. 163(3):369-376(2010)|Igreja, S., et al. Hum. Mutat. 31(8):950-960(2010)|Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
USBio References
No references available
Conjugates
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