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You are here:Home » Antibodies » Antibodies-Enzymes, Dehydrogenase » Anti -AKR1C4, NT (AKR1C4, CHDR, Aldo-keto reductase family 1 member C4, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, Dihydrodiol dehydrogenase 4, HAKRA)

Anti -AKR1C4, NT (AKR1C4, CHDR, Aldo-keto reductase family 1 member C4, 3-alpha-HSD1,
3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, Dihydrodiol
dehydrogenase 4, HAKRA)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
AKR1C4 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Catalog #031746
ApplicationsSuitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended DilutionsWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs Reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A and peptide affinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 11-39 in the N-terminal region of human AKR1C4, UniProt Accession #P17516; NP_001809.2.
SpecificityRecognizes human AKR1C4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAKR1C4, CHDR, Aldo-keto reductase family 1 member C4, 3-alpha-HSD1, 3-alpha-hydroxysteroid dehydrogenase type I, Chlordecone reductase, Dihydrodiol dehydrogenase 4, HAKRA


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