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You are here:Home » Antibodies » Abs to Protein Kinases » Anti -ALK, ID (ALK, ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246)

Anti -ALK, ID (ALK, ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2;5)(p23;q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
Catalog #031798
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
ImmunogenALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 644~673 amino acids from the center region of human ALK.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesALK, ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246


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