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031812 Rabbit Anti-ALOX12B, CT (ALOX12B, Arachidonate 12-lipoxygenase, 12R-type, Epidermis-type lipoxygenase 12)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
O75342
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_001130.1
Gene ID
242
Gene #
ALOX12B
Shipping Temp
Blue Ice
Storage Temp
-20°C
ALOX12B, Arachidonate 12-lipoxygenase, 12R-type, Epidermis-type lipoxygenase 12

This gene encodes an enzyme involved in the converstion of arachidonic acid to 12R-hydroxyeicosatetraenoic acid. Mutations in this gene are associated with nonbullous congenital ichthyosiform erythroderma.

Applications
Suitable for use in Western Blot, Immunohistochemistry and Indirect Flow Cytometry, ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Indirect Flow Cytometry: 1:10-1:50 Optimal dilution determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 622-652 in the C-terminal region of human ALOX12B. Species Sequence Homology: mouse and rat
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human ALOX12B
References
1. Han, S., et al. Hum. Immunol. 71(7):727-730(2010). 2. Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010). 3. Vahlquist, A., et al. J. Invest. Dermatol. 130(2):438-443(2010). 4. Agarwal, S., et al. Exp. Dermatol. 18(11):939-946(2009). 5. Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)
USBio References
No references available
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