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You are here:Home » Antibodies » Abs to Leukotrienes » Anti -ALOXE3, ID (ALOXE3, Epidermis-type lipoxygenase 3) (FITC)

Anti -ALOXE3, ID (ALOXE3, Epidermis-type lipoxygenase 3) (FITC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.
Catalog #031815-FITC
ApplicationsSuitable for use in Western Blot, FLISA
Recommended DilutionFLISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.
PurityPurified by Protein A affinity chromatography.
ImmunogenALOXE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the Central region of human ALOXE3.
SpecificityHuman, mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesALOXE3, Epidermis-type lipoxygenase 3


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