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031834 Rabbit Anti-AMFR, ID (AMFR, RNF45, E3 ubiquitin-protein ligase AMFR, Autocrine motility factor receptor, isoform 2, RING finger protein 45, gp78)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9UKV5
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001135.3
Gene ID
267
Gene #
AMFR
Shipping Temp
Blue Ice
Storage Temp
-20°C
AMFR, RNF45, E3 ubiquitin-protein ligase AMFR, Autocrine motility factor receptor, isoform 2, RING finger protein 45, gp78

Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
AMFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 370-400 amino acids from the Central region of human AMFR.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
References
Joshi, B., et al. J. Biol. Chem. 285(12):8830-8839(2010)|Bernardi, K.M., et al. Mol. Biol. Cell 21(1):140-151(2010)|Ballar, P., et al. Int. J. Biochem. Cell Biol. 42(1):167-173(2010)|Shmueli, A., et al. Biochem. Biophys. Res. Commun. 390(3):758-762(2009)|Ying, Z., et al. Hum. Mol. Genet. 18(22):4268-4281(2009)
USBio References
No references available
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