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You are here:Home » Antibodies » Abs to Cell Division Cycle (CDC) » Anti -ANAPC5, ID (ANAPC5, APC5, Anaphase-promoting complex subunit 5, Cyclosome subunit 5) (Biotin)

Anti -ANAPC5, ID (ANAPC5, APC5, Anaphase-promoting complex subunit 5, Cyclosome subunit 5)
(Biotin)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B FC
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
Catalog #031867-Biotin
ApplicationsSuitable for use in Western Blot, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Biotin.
PurityPurified by Protein A affinity chromatography.
ImmunogenANAPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesANAPC5, APC5, Anaphase-promoting complex subunit 5, Cyclosome subunit 5


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