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031903 Rabbit Anti-ANKRD6, ID (ANKRD6, KIAA0957, Ankyrin repeat domain-containing protein 6, Diversin)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q9Y2G4
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_055757.2
Gene ID
22881
Gene #
ANKRD6
Shipping Temp
Blue Ice
Storage Temp
-20°C
ANKRD6, KIAA0957, Ankyrin repeat domain-containing protein 6, Diversin

ANKRD6 recruits CKI-epsilon to the beta-catenin degradation complex that consists of AXN1 or AXN2 and GSK3-beta and allows efficient phosphorylation of beta-catenin, thereby inhibiting beta-catenin/Tcf signals (By similarity).

Applications
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 314-343 in the central region of human ANKRD6.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ANKRD6.
References
1. Haribaskar, R., et al. Biochem. Biophys. Res. Commun. 387(1):212-217(2009) 2. Miyasaka, K.Y., et al. Proc. Natl. Acad. Sci. U.S.A. 104(27):11274-11279(2007) 3. Schwarz-Romond, T., et al. Genes Dev. 16(16):2073-2084(2002) 4. Tissir, F., et al. Dev. Dyn. 224(4):465-469(2002)
USBio References
No references available
Conjugates
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