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Anti -ARHB, ID (RHOB, ARH6, ARHB, Rho-related GTP-binding protein RhoB, Rho cDNA clone 6)
Anti -ARHB, ID (RHOB, ARH6, ARHB, Rho-related GTP-binding protein RhoB, Rho cDNA clone 6)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E B IH |
|
| ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. | | | Catalog # | 032031 | | Applications | Suitable for use in Western Blot, Immunohistochemistry, ELISA | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:50-100 | | Immunohistochemistry: 1:10-50 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | 0.25mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS. | | Immunogen | ARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human ARHB. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | RHOB, ARH6, ARHB, Rho-related GTP-binding protein RhoB, Rho cDNA clone 6 |
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