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You are here:Home » Antibodies » Abs to CD Markers » Anti -ARHB, ID (RHOB, ARH6, ARHB, Rho-related GTP-binding protein RhoB, Rho cDNA clone 6)

Anti -ARHB, ID (RHOB, ARH6, ARHB, Rho-related GTP-binding protein RhoB, Rho cDNA clone 6)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH
ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Catalog #032031
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
ImmunogenARHB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-137 amino acids from the Central region of human ARHB.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRHOB, ARH6, ARHB, Rho-related GTP-binding protein RhoB, Rho cDNA clone 6


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