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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -ARHGDIB, CT (ARHGDIB, GDIA2, GDID4, RAP1GN1, Rho GDP-dissociation inhibitor 2, Ly-GDI, Rho-GDI beta)

Anti -ARHGDIB, CT (ARHGDIB, GDIA2, GDID4, RAP1GN1, Rho GDP-dissociation inhibitor 2,
Ly-GDI, Rho-GDI beta)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).
Catalog #032045
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenARHGDIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the C-terminal region of human ARHGDIB.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesARHGDIB, GDIA2, GDID4, RAP1GN1, Rho GDP-dissociation inhibitor 2, Ly-GDI, Rho-GDI beta


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