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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -ARHGEF18, NT (ARHGEF18, KIAA0521, Rho guanine nucleotide exchange factor 18, 114kD Rho-specific guanine nucleotide exchange factor, Septin-associated RhoGEF)

Anti -ARHGEF18, NT (ARHGEF18, KIAA0521, Rho guanine nucleotide exchange factor 18, 114kD
Rho-specific guanine nucleotide exchange factor, Septin-associated RhoGEF)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.
Catalog #032049
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenARHGEF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the N-terminal region of human ARHGEF18.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesARHGEF18, KIAA0521, Rho guanine nucleotide exchange factor 18, 114kD Rho-specific guanine nucleotide exchange factor, Septin-associated RhoGEF


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