Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Autophagy » Anti -ATG16L, phosphorylated (S287) (ATG16L1, APG16L, Autophagy-related protein 16-1, APG16-like 1)

Anti -ATG16L, phosphorylated (S287) (ATG16L1, APG16L, Autophagy-related protein 16-1,
APG16-like 1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The APG12-APG5-APG16L complex is essential for the elongation of autophagic isolation membranes. This complex initially associates in uniform distribution with small vesicle membranes. During membrane elongation, the complex partitions, with a great concentration building on the outer side of the isolation membrane. Upon completion of the formation of the autophagosome, the APG12-APG5-APG16L dissociates from the membrane.
Catalog #032181
ApplicationsSuitable for use in Dot Blot, ELISA
Recommended DilutionELISA: 1:1,000
Dot Blot 1:500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by peptide immunoaffinity chromatography.
ImmunogenPhospho-ATG16L-S287 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 272~302 amino acids surrounding S287 of human APG16L. Patent pending.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesATG16L1, APG16L, Autophagy-related protein 16-1, APG16-like 1


External Links