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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -ATRX, NT (E384) (Transcriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX, ATRX, RAD54L, XH2,)

Anti -ATRX, NT (E384) (Transcriptional regulator ATRX, ATP-dependent helicase ATRX,
X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX, ATRX, RAD54L, XH2,)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
ATRX contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. Theses mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis.
Catalog #032314
ApplicationsSuitable for use in ELISA
Recommended DilutionELISA: 1:1,000
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration0.25mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenATRX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377~406 amino acids from the N-terminal region of human ATRX.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesTranscriptional regulator ATRX, ATP-dependent helicase ATRX, X-linked helicase II, X-linked nuclear protein, XNP, Znf-HX, ATRX, RAD54L, XH2,


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