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You are here:Home » Antibodies » Abs to Amyloid » Anti -BACE2, CT (BACE2, AEPLC, ALP56, ASP21, Beta-secretase 2, Aspartic-like protease 56kD, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-sec

Anti -BACE2, CT (BACE2, AEPLC, ALP56, ASP21, Beta-secretase 2, Aspartic-like protease
56kD, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down
region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-sec

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the protein encoded by this gene. This gene localizes to the 'Down critical region' of chromosome 21. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease. Three transcript variants encoding different isoforms have been described for this gene.
Catalog #032371
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration0.25mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenBACE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 482-511 amino acids from the C-terminal region of human BACE2.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesBACE2, AEPLC, ALP56, ASP21, Beta-secretase 2, Aspartic-like protease 56kD, Aspartyl protease 1, Beta-site amyloid precursor protein cleaving enzyme 2, Down region aspartic protease, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase


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