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032621 Rabbit Anti-BTN3A1, CT (BTN3A1, BTF5, Butyrophilin subfamily 3 member A1, CD277)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
O00481
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001138481.1; NP_919423.1; NP_001138480.1; NP_008979.3
Gene ID
11119
Gene #
BTN3A1
Shipping Temp
Blue Ice
Storage Temp
-20°C
BTN3A1, BTF5, Butyrophilin subfamily 3 member A1, CD277

The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin (Ig) domains and an intracellular B30.2 (PRYSPRY) domain. Three subfamilies of human BTN genes are located in the MHC class I region: the single-copy BTN1A1 gene (MIM 601610) and the BTN2 (e.g., BTN2A1; MIM 613590) and BTN3 (e.g., BNT3A1) genes, which have undergone tandem duplication, resulting in 3 copies of each (summary by Smith et al., 2010 [PubMed 20208008]).[supplied by OMIM].

Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 345-374 in the C-terminal region of human BTN3A1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human BTN3A1.
References
1. Smith, I.A., et al. J. Immunol. 184(7):3514-3525(2010). 2. Shi, J., et al. Nature 460(7256):753-757(2009). 3. Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006). 4. Mungall, A.J., et al. Nature 425(6960):805-811(2003). 5. Rhodes, D.A., et al. Genomics 71(3):351-362(2001)
USBio References
No references available
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