CALCR, CT

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Swiss Prot

P30988

Isotype

IgG

Grade

Affinity Purified

Applications

E FC IF WB

Crossreactivity

Accession #

NP_001733.1

Gene ID

799

Gene #

CALCR

Shipping Temp

Blue Ice

Storage Temp

-20°C

CALCR, Calcitonin receptor

CALCR is a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis.

Applications

Suitable for use in Western Blot, Immunofluorescence, Indirect Flow Cytometry and ELISA. Other applications have not been tested.

Recommended Dilution

Western Blot: 1:1000 Immunofluorescence: 1:10-1:50 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.

Storage and Stability

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 445-474 in the C-terminal region of human CALCR

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human CALCR.

References

1. Nussenzveig, D.R., et al. Endocrinology 136(5):2047-2051(1995). 2. Nakamura, M., et al. Biochem. Biophys. Res. Commun. 209(2):744-751(1995). 3. Egerton, M., et al. J. Mol. Endocrinol. 14(2):179-189(1995). 4. Gorn, A.H., et al. J. Clin. Invest. 90(5):1726-1735(1992)

USBio References

No references available

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033146 Rabbit Anti-CALCR, CT (CALCR, Calcitonin receptor)

Clone Type

Host

Source

Swiss Prot

Isotype

Grade

Applications

Crossreactivity

Accession #

Gene ID

Gene #

Shipping Temp

Storage Temp

CALCR, Calcitonin receptor

References

USBio References

Conjugates

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