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You are here:Home » Antibodies » Antibodies-Calpain » Anti -CAPN6, ID (CAPN6, CALPM, CANPX, Calpain-6, Calpain-like protease X-linked, Calpamodulin) (APC)

Anti -CAPN6, ID (CAPN6, CALPM, CANPX, Calpain-6, Calpain-like protease X-linked,
Calpamodulin) (APC)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.
Catalog #033183-APC
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, FLISA
Recommended DilutionFLISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and StabilityStore product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note Applications are based on unconjugated antibody.
Clone TypePolyclonal
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2. No preservative added.
PurityPurified by Protein A affinity chromatography.
ImmunogenCAPN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 289-319 amino acids from the Central region of human CAPN6.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCAPN6, CALPM, CANPX, Calpain-6, Calpain-like protease X-linked, Calpamodulin

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