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Anti -CARD11, CT (CARD11, CARMA1, Caspase recruitment domain-containing protein 11, CARD-containing MAGUK protein 1)
Anti -CARD11, CT (CARD11, CARMA1, Caspase recruitment domain-containing protein 11,
CARD-containing MAGUK protein 1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH FC |
|
| CARD11 belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. | | | Catalog # | 033188 | | Applications | Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:100-500 | | Immunohistochemistry: 1:50-100 | | Flow Cytometry: 1:10-50 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | 0.25mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | CARD11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CARD11, between aa 1017-1029. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CARD11, CARMA1, Caspase recruitment domain-containing protein 11, CARD-containing MAGUK protein 1 |
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