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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -CASP6, NT (CASP6, MCH2, Caspase-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11)

Anti -CASP6, NT (CASP6, MCH2, Caspase-6, Apoptotic protease Mch-2, Caspase-6 subunit p18,
Caspase-6 subunit p11)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in two transcript variants that encode different isoforms. [provided by RefSeq].
Catalog #033217
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenCASP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-45 amino acids from the N-terminal region of human CASP6.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCASP6, MCH2, Caspase-6, Apoptotic protease Mch-2, Caspase-6 subunit p18, Caspase-6 subunit p11


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