Anti -CBL, CT (RING finger protein 55, Casitas B-lineage lymphoma proto-oncogene,
Proto-oncogene c-Cbl, Signal transduction protein CBL, E3 ubiquitin-protein ligase
CBL,RNF55, CBL2, CBL)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E B FC |
|
| The CBL oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation. | | | Catalog # | 033239 | | Applications | Suitable for use in Western Blot, Flow Cytometry, ELISA | | Recommended Dilution | ELISA: 1:1,000 | | Western Blot: 1:50-100 | | Flow Cytometry: 1:10-50 | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | 0.25mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. | | Purity | Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS. | | Immunogen | CBL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CBL. | | Specificity | Human | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | RING finger protein 55, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, Signal transduction protein CBL, E3 ubiquitin-protein ligase CBL,RNF55, CBL2, CBL |
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