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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -Cbx5, CT (Cbx5, Hp1a, Chromobox protein homolog 5, Heterochromatin protein 1 homolog alpha)

Anti -Cbx5, CT (Cbx5, Hp1a, Chromobox protein homolog 5, Heterochromatin protein 1 homolog
alpha)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins (By similarity).
Catalog #033255
ApplicationsSuitable for use in Western Blot, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenMouse Cbx5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-186 amino acids from the C-terminal region of mouse Cbx5.
SpecificityMouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCbx5, Hp1a, Chromobox protein homolog 5, Heterochromatin protein 1 homolog alpha


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