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You are here:Home » Antibodies » Abs to CD Markers » Anti -CCR1, NT (CCR1, CMKBR1, CMKR1, SCYAR1, C-C chemokine receptor type 1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, CD191)

Anti -CCR1, NT (CCR1, CMKBR1, CMKR1, SCYAR1, C-C chemokine receptor type 1, HM145, LD78
receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, CD191)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC
CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Catalog #033428
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenCCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2~31 amino acids from the N-terminal region of human CCR1.
SpecificityHuman
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCCR1, CMKBR1, CMKR1, SCYAR1, C-C chemokine receptor type 1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, CD191


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