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You are here:Home » Antibodies » Antibodies-CD Markers » Anti -CD105, ID (E395) (ENG, END, Endoglin, CD105)

Anti -CD105, ID (E395) (ENG, END, Endoglin, CD105)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified E B IH FC
CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Catalog #033445
ApplicationsSuitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications have not been tested.
Recommended DilutionWestern Blot: 1:1000
Flow Cytometry: 1:10-1:50
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenKLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 380-409 in the central region of human CD105, UniProt Accession #P17813.
SpecificityRecognizes human CD105. Species crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesENG, END, Endoglin, CD105


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